Synaptic Transmission - Principles of chemical synaptic transmission
5 important questions on Synaptic Transmission - Principles of chemical synaptic transmission
What proteins embedded in the vesicle membrane concentrate the proteins inside the vesicles?
The depolarization of the terminal membrane (presynaptic membrane) causes what channels in the active zones to open?
What is caused by the opening of these channels?
Results in a large inward driving force of Ca2+, the resulting elevation of Ca2+ is the signal that causes neurotransmitters to be released from the synaptic vesicles --> releases its content into the synaptic cleft
Once the released neurotransmitter has interacted with the postsynaptic receptors, it must be cleared from the synaptic cleft. Name the ways to do this:
- Reuptake
- Ezymatic destruction
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Some drugs are called receptor antagonists. What happens with the normal action of the transmitter?
Some drugs are called receptor agonists. What do they do?
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