Brain control of movement

8 important questions on Brain control of movement

What is the direct pathway of the basal ganglia? & function?

Cortical cells --> Excite putamen cells --> Putamen cells inhibit Globus Pallidus neurons --> Globus pallidus inhibits VLo (ventral lateral???) --> VLo excites the SMA (plaatje beter)

Funtion
- Discharge of movement related cells
- Enhance intiation of desired movements
- Go signal by boosting SMA

What is the indirect pathway of the basal ganglia? & Function?

Striatal neurons --> Inhibit GPe cells --> Inhibites the cells of the GPi & Subthalamic nucleus --> Cortex excites the Subthalamic nucleus --> Projections excite the GPi neurons, which inhibits the thalamic neurons (plaatje is chiller)

Function::
- Antagonize motor functions of direct pathway
- Thalamus inhibition
- Supression of competing, inappropriate motor programs

How does M1 code for voluntary movement? (activity)

1 cell = 1 vote for certain movement
Direction of movement = Average

- So we can predict movements by population vectors
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What do we mean with the Malleable motor map?

M1 neurons can change their movement preference when a new skill is learned

- Reorganization is possible

What is coolio about the anatomy of the cerebellum?

Peduncles rise from the pons with a high density of the neuronal axons

A lot of Folia (folds) & Lobules (areas): A LOT of surface area

What does the lateral cerebellum control?

Limb movements

Besides fine motor control, what is the function of the cerebellum?

Motor learning.

Motor loop:
- Get a lot of input --> What did i want to do --> What actually happened

What is cerebellum programming?

Creation of new motor porgrams

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