Neuron-glia plasticity
8 important questions on Neuron-glia plasticity
Which glial cells can regulate neuronal plasticity?
- Schwann cells (CNS)
- Oligodendrocytes (CNS)
- Astrocytes (CNS)
- Microglia (CNS)
What is true about myelin plasticity?
- Myelination continues into adulthood
- Learning increases myelination
- Action potentials induce myelination
How can myelin fine-tine the velocity of action potentials?
- Thickness/compaction of myelin (changing electric isolation)
- Length between nodes (internodes)
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Which signal determines myelin thickness during development?
What are two pathways that are activated by NRG1 type III?
- RAS: RAF: proliferation of Schwann cells
- P13K: AKT: differentiation and myelination
What is Botulinum toxin (BnTx)?
What is the difference between intrinsic and adaptive myelination?
Adaptive is myelin plasticity, depends on axonal activity and learning.
What is special about astrocytes (neuron-glia interactions)?
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