Preventing muscle ageing

6 important questions on Preventing muscle ageing

In which ways can the mitochondira be improved?

  • Exercise works
  • resistance
  • endurance
  • concurrent
  • HIIT / power (image)


Nutrition ... Not so much work done yet

  • PUFA: no effect shown yet
  • resveratrol
    • PL, pre-training
    • PL, post-training
    • RSV, pre-training
    • RSV, Post-training -> higher
  • Epicatechin


Potential for vitamin B3, B6, B9, B12 / PUFA / phospholipids

What does ursolic acid do?

Ursolic acid induces skeletal muscle hypertrophy

prevend furter muscle mass loss

The trail
  • standard care vs novel product
  • 12 weeks
  • close eye on them, weight, DEXA scanner, physical functioning


What were the results and conclusions?

  • Body weight increases
  • Fat mass increases more with standard care
  • Improved walk speed
  • No effects on other functional outcomes


conclusion
  • A novel oral nutritional supplement
    • containing whey + casein protein, ursolic acid, additional BCAAs and vitamin D
  • Improves gait speed
    • as compared to standard care in community-swelling older adults, driven
  • by improved mitochondrial functioning
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The protein (and exercise) to improve muscle mass - ProMuscle
four arms
  • Placebo
  • Protein (30g/d)
  • Resistance Exercise (2x per week)
  • Protein + exercise


What are the results?

PRO vs placebo
  • just 30 grams extra protein per day is not enough

Exercise vs exercise + PRO
  • There is effect, when also protein was taken in the lean body mass increased
RE
  • everyone is responding

RE + PRO: lean body mass
  • inprovement with protein intake, not in every study

RE + PRO: muscle mass
  • there is a small improment but it is not significant

RE + PRO: strength
  • improvement but not significant


In conclusion:
  • Resistance exercise definitely works
  • Standard treatment against sarcopenia
  • Protein might increase responses to resistance exercise

The protein (and exercise) to improve muscle mass - ProMuscle
four arms
  • Placebo
  • Protein (30g/d)
  • Resistance Exercise (2x per week)
  • Protein + exercise


What are the results?

PRO vs placebo
  • just 30 grams extra protein per day is not enough

Exercise vs exercise + PRO
  • There is effect, when also protein was taken in the lean body mass increased
RE
  • everyone is responding

RE + PRO: lean body mass
  • inprovement with protein intake, not in every study

RE + PRO: muscle mass
  • there is a small improment but it is not significant

RE + PRO: strength
  • improvement but not significant


In conclusion:
  • Resistance exercise definitely works
  • Standard treatment against sarcopenia
  • Protein might increase responses to resistance exercise

Decreasing intramuscluar adipose tissue, what works?

Exercise works
  • resistance
  • endurance
  • concurrent

Nutrition might work
  • protein & vitamin D (image)


6 month 20mcg Vit D + 20 g Whey PRO
Plus 3x/w concurrent exercise

The question on the page originate from the summary of the following study material:

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