NP12 Energetic efficiency, heat production

8 important questions on NP12 Energetic efficiency, heat production

What is part of the oxygen transport system?

  • Pulmonary ventilation
  • Hemoglobin concentration
  • Blood volume and cardiac output
  • Peripheral blood flow
  • Aerobic metabolisme

What is the efficiency (%) from glycogen, protein and fat looking at aerobic metabolism

glycogen
  • 36%
  • 64%
protein
  • 35%
  • 65%
fat
  • 35%
  • 65%

What are the differences in substrate use?

  • The body as a whole is aerobic
  • The body in balance (N=0, E=0) dietary intake is oxidised completely
  • Shifts in substrate use can have physiological advantages
    • on the short term (sprint)
    • locally in the body
    • but with possible consequences for Eefficiency (decreases ?)
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ATP: aerobic --> anaerobic

  • Contribution an-aerobic ATP increases
  • Ration ATP anaerobic : aerobic --> 1:14
  • Anaerobic ATP production > 7% of total
  • Initially nett lactate production
  • Discriminatie between short and longer term

What happens with high altitude exposure [unavoidable]

  • Hypobaric conditions cause hypoxia (los O2) with ATP-production via anaerobic glycolysis (lactate!)
  • Anaerobic glycolysis needs support of gluconeogenesis from lactate (Cori-cycle).
  • Energy expenditure increases, thus O2 consumption needs to increase --> problem appearing...

What happens in unavoidable conditions (longer term) (with lower O2)

  • Contribution an-aerobic ATP increases
  • Ratio ATP anaerobic:aerobic > 1:14
  • Anaerobic ATP production > 7% of total
  • Nett production of lactate
  • Lactate has to be cleared immediately when it is produced

BMR - basal metabolic rate =

  • Energy expenditure in the post-absorptive state
  • measured under conditions of thermal neutrality
  • awake but completely at rest


The energy cost of maintaining
  • circulation and breathing
  • nerve and muscle tone
  • metabolic homeostasis

RMR - resting metabolic rate =

  • Energy expenditure at rest
  • not measured under strictly controlled conditions

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