Rheumatoid arthritis - Medical treatment of RA
7 important questions on Rheumatoid arthritis - Medical treatment of RA
What are the goals of (medical) interventions in the early stages of RA?
- Slow down disease progression
- reduce pain
- eliminate unnecessary anxiety
- prevent maladaptive behaviour patterns
What drug treatment can be used in the early stage of RA?
- Use of immunosuppressive medication, to prevent/slow down joint damage.
- DMARDS = disease modifying anti-rheumatic drugs
- After that the use of anti-TNF (specific element intervening on the inflammation process)
What drug treatment can be used to target pain and/or inflammation in RA?
- Non-steroidal anti-inflammatory drugs (NSAIDS; ibuprofen), cortisone, steroids
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What are possible side-effects of DMARDS
- Upset stomach (nausea, diarrhea)
- fatigue
- headache
- liver damage
- vulnerability to infection
What are possible side-effects of NSAIDS?
- Gastro-intestinal problems (ulcers)
- higher risk at CVD/stroke
What is the effect of medication side-effects on medication use?
What are possible barriers for patients to adhere to physical activity recommendations?
- Pain/disability/depression
- failure to see benefits
- maladaptive beliefs about exercise
- environmental factors
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