Summary: Parkinson's
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Read the summary and the most important questions on Parkinson's
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1 History and Demographics
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What is the incidence for Parkinson's in the UK?
1/500 -
At roughly what age is the majority of people diagnosed?
50s -
Which gender is more susceptible
Men -
Is it a progressive or regressive condition?
Progressive -
Where is dopamine produced?
substantia nigra located in the basal ganglia -
Parkinsons are evident when about....of the dopamine producing neurones are lost.
80% -
The pars compacta substantia nigra has an important role in....
motor control, motivation, arousal and reward -
Dopamine cannot cross the blood brain barrier, but ......can
L-dopa -
Outside of the central nervous system (CNS) it acts on....
vasodilation, increases urine output, reduces insulin production and gastrointestinal motility. -
Give 4 motor symptoms of Parkinson's
Muscle weakness
Festinating gait
Freezing of gait
Loss of facial expression
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