Intravenous infusion and multiple dosing
13 important questions on Intravenous infusion and multiple dosing
What is a distribution phase?
What is curve stripping?
This will tell you something about the speed of the distribution. Also halflife can be read from this curve.
With more compartments involved, the volume of distribution will become more complicted:
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How does an orally given graph look like?
What is a relative bio-availability?
Bio-availability is never calculated for intravenous administration. But all other ways can be calculated.
How does an infusion graph look like?
After 5 halflifes, the steady state will be reached.
How to calculate the steady state?
What to do in accute situations?
Why do formulations differ?
Threre are therapeutic reasons and pharmaceutical, technical or economical reasons.
Where do formulations differ?
Tablets are the most liked administer of drugs, but how are they made?
What are the reasons for layerd tablets?
Controlled release
It has different effects in the gastro- intesitnal tract
pharmacokinetic properties
therapeutical reasons
What is an osmotic tablet?
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