Heart failure - Blood pressure control
7 important questions on Heart failure - Blood pressure control
What is the myogenic response of autoregulation?
=> stretching of vascular smooth muscle cells causes depolarizatoin of SMCs > contraction > reduction of vascular diameter.
This mechanisms counteracts pressure induced changes in vascular diameter. Therefore the pressure in capillary remains the same.
Why is there also extrinsic control of blood vessels?
To allow the brain to alter blood flow selectively to individual organs
Which receptors and effects are important in neural control of the vessels?
Parasympathetic = ACh
NA binds to alfa receptors on bv which causes vasoconstriction or to ß receptors which causes vasodilatation
ACh binds to M2 receptors -> vasodilatation
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What is the effect of NAd and ACh on the heart?
ACh - decreased inotropy, chronotropy and dromotropy & inhibits release of NAd
When is adrenaline produced and by which organ?
How does the RAAS system work?
What is the primary role of baroreceptors?
- Blood flow to the brain & myocardium must be maintained at all costs.
- It is essential, therefore, to maintain arterial blood pressure in the carotid and coronary arteries.
- Blood pressure sensors have evolved in the walls of the carotid arteries and aorta, to inform the brain of the pressure in these key feeder vessels.
- The sensors, BARORECEPTORS, actually detect wall stretch, which increases with pressure
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