Volume regulation
6 important questions on Volume regulation
What is volume regulation?
What does adding/removing of NaCl mainly affect?
How are changes in ECV sensed?
- low pressure baroreceptors (very important)
- cardiac atria
- pulmonary vasculature
- high pressure baroreceptors (less important)
- carotid sinus
- aortic arch
- juxtaglomerular apparatus (renal afferent arteriole)
- sensors in the CSN (less important)
- sensors in the liver (less important)
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What are main pathways that influence the EffCV?
- RAAS
- Sympathetic nervous system
- Atrial natriuretic peptide (ANP)
- Arginin vasopressin (AVP) = antidiuretic hormone (ADH)
How can RAAS be blocked?
NSAIDs
beta blockers
angiotensin receptor blockers
disease
aldosterone receptor blockers
sodium channel blockers
How can RAAS be blocked?
NSAIDs
beta blockers
angiotensin receptor blockers
disease
aldosterone receptor blockers
sodium channel blockers
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