Cardiac functions and energetics

3 important questions on Cardiac functions and energetics

How is the stiffness calculated (S)?

S = dF/dL

F = force
L = length

In the muscle we talk about force-length relationship, but in the heart this is something else, what?

Pressure-volume relationship

What reduces cardiac output (stroke volume)?

Reduced preload
Increased afterload
Reduced inotropy
Reduced lusitropy  

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