Positive psychiatry: Its time has come

21 important questions on Positive psychiatry: Its time has come

What is positive psychiatry?

Science and practice of psychiatry that seeks to understand and promote well-being through assessment and interventions involving positive psychological characteristics (PPCs) in people who suffer from or are at high risk of developing mental or physical illnesses.

What is the main aim of positive psychiatry?

Greater well-being, achieved through optimal increase in key PPCs. Research in psychiatry is focused on the biological underpinnings of PPCs.

What are the main components in positive psychiatry? (4)

1. Positive mental health outcomes
2. PPCs that comprise psychological traits and environmental factors
3. Biology of positive psychiatry constructs
4. Positive psychiatry interventions (including preventive ones)
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What are the dimensions and targets of a positive psychiatric approach? (6)

1. Well-being
2. Low level of perceived stress (believe that contemporary demands or challenges exceed the ability to cope)
3. Successful psychosocial aging (ability to adapt to circumstances and positive attitude to the future)
4. Post-traumatic growth
5. Recovery in serious mental illness
6. Prevention of mental illness

What are positive psychological traits? (6)

1. Resilience (recovery from or positive adaptation to adversity)
2. Optimism (tendency to expect good outcomes
3. Personal mastery and coping self-efficacy (self-perceived ability to activate specific coping strategies to overcome life challenges and to influence outcomes)
4. Social engagement (level of integration into a social network (number, quality, frequency, and degree of pleasure)
5. Spirituality and religiosity (the extent to which a person focuses on transcendent topics)
6. Wisdom

What are positive environmental factors? (2)

1. Family dynamics (can impact symptom severity, response, and possibility of recovery)
2. Social support (degree to which people are available for emotional/physical support)

What are possible other determinants of psychosocial functioning? (3)

Availability of regular medical care, opportunities for activities, and adequate nutrition.

What are the potential biomarkers of positive mental health? (2)

1. Allostatic load (cumulative physiological response to frequent and sustained exposure to environmental stressors)
2. Telomere length (indicator of biological age; cumulative index of the number of cell divisions and exposures to genotoxic and cytotoxic processes such as oxidation)

What are the factors that can influence telomere length? (3)

1. Perceived stress is more critical than objective measures of stress
2. Healthy lifestyle changes and psychosocial stress reduction can increase telomerase activity
3. Prolonged oxidative stress

What is known about the general biology of resilience and optimism? (3)

1. Partially heritable
2. Candidate genes in the limbic and prefrontal cortex (optimism linked to oxytocin receptor gene and a variation of a gene responsible for serotonin transport)
3. Genes and their reaction with the environment may shape the neural circuitry and neurochemical function expressed in psychological traits

What is known about the general biology of personal mastery and coping self-efficacy? (2)

1. Reduced personal mastery resulting from chronic stress may provoke excessive activation of the autonomic nervous system, which can affect immune functioning
2. Greater coping self-efficacy is associated with lower blood pressure and pulse pressure, and a low coping self-efficacy with pro-inflammatory IL-6

What is known about the general biology of social engagement?

There is ambivalence about one's social relations being associated with shorter telomeres

What is known about the general biology of spirituality and religiosity?

It is associated with better lipid profiles, lower blood pressure, better immune function and decreased levels of cortisol

What is known about the general biology of wisdom (including compassion?

A mutation of a gene related to the tau-protein on chromosome 17 elicits a loss of behavioural characteristics comprising wisdom: especially compassion and empathy

Why is it interesting that the focus thus far has been on the disease model in child/adolescent psychiatry?

Because there is evidence that most of the core domains of child psychopathology exist along broad spectrums with few qualitative boundaries. Besides, there is evidence that positive psychiatry can improve the functioning of children with or without significant psychopathology.

What is known about neuroplasticity in aging populations?

That is can be maintained to a degree, enabling PPCs to affect individuals' health throughout the lifespan and improve functioning for them.

What lifestyle interventions can be encouraged? (4)

1. Exercises to help (prevent) depression, improve impulse control, attention, and arousal, and help reduce learned helplessness
2. Meditative practices to enhance positive affect, and decrease anxiety and negative affect. Besides, it has benefits across a range of psychiatric conditions
3. Healthy diet to reduce risk of depression
4. Sleep to improve quality of life

What can be the advantages of positive psychiatry in clinical practice? (5)

1. It has value for several psychopathological conditions (incl. schizophrenia)
2. Positive interventions can complement medication or psychotherapy
3. Convenient and cost-effective
4. Less stigma associated with positive interventions
5. May help to buffer against relapse

What are social/political/ethical limitations to positive psychiatry

1. Objections to optimism being promoted through biological or other interventions
2. Less consensus about what constitutes positive mental health, and about which clinical interventions may be efficacious (compared to mental illness)

What are the scientific/academic limitations to positive psychiatry? (4)

1. Many larger funding agencies tend to be oriented towards illnesses and thus the ability to generate date on positive outcomes may be limited
2. No clinical mandate to define the constructs of positive outcomes
3. Potential for adverse effects of PPIs (wording in a PPI can have a negative impact)
4. There should be clarity about whether interventions promote hedonic or also eudaimonic experiences

What should future research in positive psychiatry focus on? (3)

1. Include knowledge beyond mental illness so that it encompasses the full range of health
2. Better operalizations and better assessment of positive psychological psychosocial outcomes and PPCs
3. If clinicians would also focus on evaluating measures of well-being, interventions could be employed to enhance to traits, focusing on positive outcomes (e.g. well-being and recovery)

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