Dirk Hilbers - Ethical aspects animal experiments

12 important questions on Dirk Hilbers - Ethical aspects animal experiments

What are the status quo - policy of animal testing?

  • Animals - some moral status, but Humans - higher status
  • Testing animal is morally problematic but not necessarily morally rejectable
  • Law on animal testing: "Prohibited unless"-ruling (Vaccination testing)
  • Testing is prohibited unless the institutions say otherwise. Ethical consensus is not an objective truth. In society - public must be informed.

What is the extrapolation problem "non-ethical consideration in the debate"? What is a contra argument you could give?


  • Animals are not a perfect model for humans, sometimes a bad model
  • alternative (in-vitro human tissue, organdies, computer models) are promising as replacement
  • Scientific (non-ethical) criticism on animal testing




(Contra argument - Scientific reason: mice vs human (physically not same as human), but in clinical trail animal testing results similar in human trails.)

Explain how a animal experiment is being requested in the Netherlands

CCD: Centraal Orgaan Dierproeven

DEC: Dierexperimentencommissie
WoD: Wet op Dierproeven
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When is animal testing never allowed?

  • When carried out by facility without a license
  • When the harm to animals is higher than is necessary for the achievement of the research targets

What is a humane end point when doing experiments with animals?

A clearly defined point-of-harm is when animals are taken out of the experiment - by killing it


Harm vs benefit are they morally justified or not?

How would you summarise weighing harm?

  • The amount of harm depends on the severity, frequency and duration of effect. Effect stretches out to all aspects of the animal's wellbeing.
  • 3 R's applied to ensure absence of unnecessary negative effects


= level of discomfort, from mild to severe

What are the four categories of "discomfort"? What is special about one of them?

Mild - Moderate - Severe - non-recovery

Non-recovery is considered "less bad" then mild, because animal don't feel (actual death of animal is not considered as harmful)

What are the human benefit of animal experiments, their interests?

  • Scientific interests: the advance of a filed of science
  • Societal interest: the improvement of health care, the environment or other social advances

On what is the human benefit determined by?

  • Impact on survival, quality of life, suffering
  • Efficiency, safety
  • Number of patients with disease
  • Uncertainty

What are immediate goals?

Direct results form the test

What are ultimate goals?

What one hopes to accomplish by doing the test

What does the Bateson's cube of weighing discomfort consider? What is missing in the Bateson's cube

  • Benefits (low/high)
  • Likelihood of benefit (low/high)
  • Harm to Animals (low/high)


Missing
  • 3 R's
  • Number of animals

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