Propagated Signaling: The Action Potential - Voltage-Gated Sodium and Potassium Conductances Are Calculated From Their Currents

3 important questions on Propagated Signaling: The Action Potential - Voltage-Gated Sodium and Potassium Conductances Are Calculated From Their Currents

By which two factors is the current flow of Na+ and K+ most modulated?

  1. Conductance of channels
  2. Electrochemical driving force

What are the main differences between voltage gated Na+ and K+ channels?

Na+ open more rapidly in response to depolarizing changes in voltage.
Na+ channels become inactive after some time during the depolarization, K+ stays open for the whole duration of depolarization.

What are the three states a voltage gated Na+ channel can be in?

  1. resting
  2. activated (first depolarization encounter)
  3. inactivated (prolonged depolarization)

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