Synaptic integration - Excitatory and Inhibitory Signals Are Integrated Into a Single Response by the Cell

3 important questions on Synaptic integration - Excitatory and Inhibitory Signals Are Integrated Into a Single Response by the Cell

Which factors determine the net effect of excitatory and inhibitory synaptic currents?

  • distance to travel
  • axial resistance
  • membrane resistance
  • membrane capacity
  • time course
  • size and shape of synapse

Why is the net effect of synaptic potentials evaluated and most important at the axon hillock?

Here the density of voltage gated Na+ receptor is largest and therefore the neuron is there best excitable.

Which two passive membrane properties influence the excitability of a neuron?

  • Length constant
  • Time constant

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