Local Signaling: Passive Electrical Properties of the Neuron

5 important questions on Local Signaling: Passive Electrical Properties of the Neuron

The Goldman equation provides information about the resting mebrane potential given the concentrations of ions inside and outside the cell. Information about what does it not give?

Changes in membrane potential as a response to a stimulus.

What are the three most important passive electrical properties of neurons in electrical signaling?

  • membrane resistance
  • membrane capacitance
  • intracellular axial resistance

What do the three passive electrical properties of neurons influence during electrical signaling?

  • speed of transmission
  • time duration of transmission
  • amplitude of transmission
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Why are large diameter neurons easier excitable?

High length and time constant because of high Rm and cm and low rin.

How is the velocity of the action potential propagation influenced?

  • axon diameter
  • myelinization

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