Local Signaling: Passive Electrical Properties of the Neuron - Input Resistance Determines the Magnitude of Passive Changes in Membrane Potential

3 important questions on Local Signaling: Passive Electrical Properties of the Neuron - Input Resistance Determines the Magnitude of Passive Changes in Membrane Potential

If a neural membrane increases it's resistance (for example by myelinating the axon), what will happen to the voltage change when the neuron is steadily stimulated?

The resulting voltage change will be larger, as V = I * R, If R increase and I stays the same, V also increases.

What determines the input resistance (Rin) of a neuron?

  1. Neural diameter
  2. density of ion channels

What determines the specific membrane resistance of a piece of neural membrane?

  • conductance of channels
  • density of channels

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