Kaartjes
7 important questions on Kaartjes
What are serine-type proteinase inhibitors?
Molecules with a specific serine residue, for example present in soybeans and potatoes
How is growth inhibition caused by protease inhibitors?
Trypsin is an essential protease in the human body and very methionine rich. If proteins are not broken down, it cannot be formed, like other proteins. Inhibition of those also decrease uptake of S and N
How can protease inhibtors supress cancer?
Without protein digestion, no poly-ADP-ribosylation can take place which supresses the formation of ROS
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What is a aglycon?
A glycoside with toxic properties
What are cyanogenic glycosides?
glycosides that may release hydrogen cyanide
In which forms can the human body prevent HCN intoxication?
up to 10mg are bound in blood and thereby neutralized, thereby forming SCN. Howevery, SCN can compete with iodide in thyroid, causing formation of a goitre
What are fava glycosides?
aglycons causing a fatal haemolytic disorder (favism) in people with low G6PD.
Examples are vicine and convicine from broad beans
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