Bacterial Defence Against Host Immune System - Ability of pathogens to avoid or overcome phagocytosis

5 important questions on Bacterial Defence Against Host Immune System - Ability of pathogens to avoid or overcome phagocytosis

Group A Streptococci

Make a capsule composed of hyaluronic acid, the ground substance of connective tissue.

K antigen or analog Vi antigen

E. Coli and Salmonella typhi respectively

5 different methods to prevent engulfment

1. Protein A
2. O polysaccharide
3. Slime layer
4 Polysaccharide capsules
5. M-protein or fimbrae
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M. Turberculosis prevents this by

Cell wall components (sulfatides)

Catalase and Superoxide dismutase

In S. Aureus and B. Abortus these are ued to neutralize the toxic oxygen radicals in the phagolysozome

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