Pregnancy and parturition

19 important questions on Pregnancy and parturition

There are 2 cases of progesterone production, what are those cases and in which animal does it occur?


Case 1
Progesterone produced by the placenta, in sheep
Case 2
Progesterone produced by the corpora lutea, in pig/goat/cow

What causes that oestrogen dominance occurs and what does oestrogen do?

Progesterone dominance, and ...
  • oestrogens stimulate the production of PGF2a by the uterus.
  • Softening the ligaments
  • Increased secretion of viscous mucis
  • Lubrication of the birth canal

What happens with foetal mummification?

Respoption of the allantoic and amniotic fluid, dehydration of the foetus and membranes, involution of the uterus
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What are causes of foetal mortality?

Infections, stress, nutritional factors, chromosomal aberrations, insufficient blood supply, placental insufficienty

What are environmental factors that cause of embryonic mortality?

  • Age
  • Feeding
  • Timing of insemination
  • The intra-uterine environment
  • Stress

Which factors affect foetal growth?


Genetic factors
Environmental factors
Endocrine regulation -->
Insulin and IGF-1

What is the first organ that reaches maximal growth and what organs follow?

Central nervous system, skeletal system, muscular, adipose tissues

Which phases are there in prenatal growth and explain them?

Embryonic phase: Formation of the embryonic membranes, placentation, initial formation of organs tissues and systems within the embryo


foetal phase: Longest period, growth of the foetus, the placenta and the uterus

What are the 4 main functions of the placenta?

  1. Respiratory organ -> oxygen and carbondioxide
  2. Exchange of nutrients and metabolites
  3. Endrocrines
  4. Immunological barrier

How does the embryo gets oxygen rich blood?

Foetal umbilical artery with oxygen poor blood -> 2 foetal umbilical veins with oxygen rich blood

How does 2 parallel blood circulation works in a placenta?

1 circulation for the embryo, 1 for the mother

What kind of type of placenta do the horse have?

Diffuse epithelio-chorial type with a lot of microvilli, microcotyledones and microcaruncles

What is the difference between sheep and cows cotyledones and caruncles?


sheep
: Cotyledones are spherical, caruncles cup shaped
Cow:
Cotyledones are cup shapen and lie over spherical caruncles

What kind of type of placenta do ruminants have?

A cotyledonary epithelio-chorionic type

What is present in the difusse epithelio-chorial placenta of the pig? What is this?


Areaolae:
These are places where the uterine glands empty intro a space between the chorion and the uterine epithelium

What are the 5 types of maternal tissue in direct contact with the chorion and in which animals?


Epithelio-chorial
Horse, pig, ruminants,
6 tissue layers
Syndesmo-chorial
Ruminants,
5 tissue layers
Endothelio-chorial
Carnivores
4 tissue layers
Haemo-chorial
Primates, humans, rodents
3 tissue layers
Haemo-endothelial
Rabbit
1 tissue layer, direct contact with maternal blood

What are the 2 implantation types and what are their functions concerning blastocyst?


Superficial implantation:
-Farm animals, blastocyst remains in the uterine lumen. Blastocyst enlarge before attaching to epithelium of the uterine lumen
Interstitial implantation:
-Human and rodents, blastocyst remain small and implants itseld in a uterine fold of the uterine mucosa

How do the 4 extra embryonic membranes develop?

Amnion:

Originates from the mesoderm and trophoblast that grow over the embryonic disc


Yolk sac:
Already present, endodermal in origin



Chorion:
-Consist of trophoblast and mesoderm


allantois:


Arises from an extension of the yolk sac close to the embryonic disc

Why does the placentation of a horse start around day 37?

In the horse there is no elongation phase.

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