Hematopoietic and lymphoid systems

5 important questions on Hematopoietic and lymphoid systems

Anemia is classified according to underlying mechanisms that can result in anemia. Name these.

  1. Blood loss/bleeding (hemorrhage)
  2. increased red cell destruction (Hemolytic Anemias)
  3. decreased red cell production

What is Polycythemia / erythrocytosis?

an increase in red cells per unit volume of peripheral blood.

What can cause decreased white cell production in Leukopenia?

  • Bone marrow hypoplasia (chemotherapy, aplastic anaemia)
  • Drugs
  • Neoplastic proliferations: lymphoma, metastasis
  • Myelodysplastic syndrome (neoplasic disease of the bone marrow)
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What can cause Increased white cell destruction in Leikopenia?

Severe infections that trigger immune mediation.

Wanneer zie je een paracortical hyperplasia?

  • Virale infecties
  • Reactie op vaccinatie


Je hebt in deze situaties juist veel T-lymphocyten nodig en dus overstemd dit de B-cel follikels.

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