Central nervous system - Neurodegenarative diseases

4 important questions on Central nervous system - Neurodegenarative diseases

A pathologic process shared by most neurodegenerative diseases serve as histologic hallmarks of specific disorders. What is this shared pathologic proces?

accumulation of protein aggregates

What is the difference between Aβ and tau accumulation?

Aβ accumulates extracellularly
tau accumulates intracellularly

What is Parkinson disease (PD)?

a neurodegenerative disease marked by a hypokinetic movement disorder that is caused by loss of dopaminergic neurons from the substantia nigra.
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What is Huntington disease (HD)?

an autosomal dominant movement disorder associated with degeneration of the striatum (caudate and putamen)

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