Development of the gastrointestinal tract

4 important questions on Development of the gastrointestinal tract

When there is a problem in the formation of the foregut, what other problems can this cause?

Because in the primitive foregut there is only one channel from which both the digestive and the respiratory systems develop, this can also lead to respiratory problems.

What could happen in case of intestinal (mal)rotation?

When the midgut is rotating, there can be a twist in the arterial supply of the intestines, causing shortage of blood supply and ischemia of the intestines.

What is vitelline duct remnants (overblijfselen)?

The vitelline duct is the connection between the midgut and yolk sac, and usually disappears in the 8th week of embryonix development. When this connection remains, it can result in a number of pathologies. In vitelline umbilical fistula, there is a connection between the intestines and umbilicus, causing stools (ontlasting) to be found in the umbilicus. Meckel's diverticle contains ectopic gastic or pancreatic mucosa.
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What is Hirschprung's disease?

This is a defect of the neural crest, where there is an absence of the parasympathetic ganglia in the affected walls of the colon - both in the submucosal plexus and the myenteric plexus.

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