Summary: Skeletal Muscle Chapter 14
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Read the summary and the most important questions on Skeletal Muscle Chapter 14
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1 Embryonic origins and fetal development
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From which embryonic cell layer are skeletal muscles cells derived?
The embryonic mesodermal layer -
What are the precursors of satelite cells?
myoblasts that retain mitotic potential. -
Name the order of development of a muscle cell from stem cell to myofiber.
- mesodermal stem cell
- myoblast
- primary myotube
- secondary myotube
- myofiber
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What is special about the connection between primary and secondary myotubes?
They share the same basement membrane, until further development seperates the tubes by personal membranes. -
The soleus has mainly slow twitch fibers, what is thought about the origin of the soleus myofibers?
They probably originate from primary myotubes. -
When during the gestation period are the first contractile elements formed?
Around the ninth week of gestation. -
Which factors initiate the transition from myoblasts to myotubes?
myf genes like myf5, myoD, MRF4 and myogenin -
Which factor inhibits the transition from myoblast to myotube?
Myostatin, it inhibits the function of myoD -
When during the gestation do myotubes start to proliferate?
From 11 weeks onward -
When during the gestation do tertiary myotubes occur?
Around the 16th week.
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Topics related to Summary: Skeletal Muscle Chapter 14
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Embryonic origins and fetal development
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Connections between nerve and muscle - First contact
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Connections between nerve and muscle - Loss of multiple innervation
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Muscle growth during childhood and adolescence
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Ageing and muscle function
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Influence of chronic activity
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Overload and strength training
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Adaptation to decreased muscle use - Immobilization
