Embryonic origins and fetal development

3 important questions on Embryonic origins and fetal development

Why are primary myotubes well related to slow twitch muscle fibers?

They alone express the MHC I type, which is strongly associated with a slow muscle fiber type.

When during gestation do nerve cells make contact with the newly formed myotubes?

At week 10

What is the effect of innervation to muscle fiber contractile element expression?

The stimulation by the nerve can elicit changes in the expression of MHC and light chain proteins as apparant from the fading of embryonic MHC and rise of adult MHC.

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