Connections between nerve and muscle - First contact
3 important questions on Connections between nerve and muscle - First contact
How many motorneurons innervate one muscle fiber?
Depends on the state of maturation, in the embryo, every axon innervates a muscle fiber. When the human matures, many connections are lost until only 1 motorneuron axons innervates 1 muscle fiber.
Where are the adult receptors for AChR located?
At the basement membrane of the muscle fibers (neuromusculair junctions)
What makes nuclei just underneath the neuromuscular junction different in their gene expression compared to other muscle nuclei?
They express the AChR as they are stimulated to do so by calcitonin gene-related peptide.
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