Constructing neuronal circuits
5 important questions on Constructing neuronal circuits
What are 4 requirements for the formatting of a neuronal network
- Establish polarization
- neurite outgrowth
- synaptic contact
- stabilization of the contact
What happens when there is an attractive cue
What happens when there is a repulsive cue
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What happens when there is inside-out signaling from the integrins
Name the 5 steps of synapse formation
- Outgrowth makes contact with axon due to cadherins
- insertion of the active zone
- pre and post align --> neurexin and neurligin
- EphB activation --> post synaptic receptor insertion
- synapse maturation
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