DNA damage in aging
15 important questions on DNA damage in aging
What happens with life expactancy and time?
What are environmental causes of dna damage?
What are endogenous causes of dna damage?
Alkylation
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How many dna lesions are there everyday?
What is NER and how does it work?
What is transcription coupled NER?
What are the three inherited diseases, which prevent NER from working?
Cockayne syndrome
Trichothiodystrophy
What is xeroderma pigmentosum?
What is cockayne syndrome?
What is a main hallmark of aging?
What happened in the Ercc delta mice?
Decline spatial learning
Progressive motor abnormalities
Reduced LTP
So basically all symptoms of alzheimers
How many significantly changes genes were identified in the cortex?
What are braak stages?
Why was dietary restriction so useful in ercc1 delta mice?
What was the effect seen in mice of dietary restrictions?
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