Neurodevelopmental disorders of the brain
17 important questions on Neurodevelopmental disorders of the brain
What are critical periods?
For what are critical periods key?
Correction of some sensory impairments
What are neurodevelopmental disorders?
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What has a high comordity along asd?
What are underlying causes of neurodevelopmental disorders?
Brain trauma & physical injury
Metabolic disorder & nutritional factors
Toxins & environmental conditions
Genes- chromosomal abnormalities
What is valproic acid and how can it influence neurodevelopment?
How many genes are linked to ID and asd?
And 400-1000 genes to asd
What is a hallmark pattern in neurodevelopmental disorders?
What are immature spines like and mature?
Where do many genes underlying ndds act upon?
What are the three biological functions of synapses?
2. Cytoskeletal/structural proteins
3. Translational/transcription of new proteins
What do the presynaptic ID genes do?
What do postsynaptic ID genes do?
What are characteristics of the fragile x syndrome?
Hyperextensible joints
Low muscle ton
Macroorchidism
To what gene is fragile x syndrome linked to?
What is mGlur theory?
What are the two main hypotheses for NDD's?
2. Developmental delays: critical period brain disorders
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