Alzheimer disease
8 important questions on Alzheimer disease
What are neurodegenerative diseaes
What are most ndd's associated with?
What are the cognitive impairments in Alzheimers?
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What is the life expectancy after diagnosis of AD?
What is the ad neuropathology?
Enlargement of cerebral ventricles and brain sulci
30-40% reduction in brain weight
Plaques
Tangles
Which neurons eventually die in AD?
Glutamergic pyramidal cells in cortext-> cognitive deficits
Noradrenergic and serotonergic neurons
Why are plaques thought to be not so problematic?
What can be concluded from mice experiments?
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