Summary: The Truth In Our Bones Week 2
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Read the summary and the most important questions on The Truth in our Bones Week 2
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1 Paleopathology: Introduction
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Why is it hard to assess health?
- Because we are never completely
healthy - There is no single
definition of health
- Because we are never completely
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What does the term acquired conditions mean and what do these consist of?
- Conditions obtained during life
- These consist of:
- Trauma
- Infectious disease
- Joint disease
Metabolic conditionsNeoplastic conditions (cancer, dental disease)
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What does the term congenital conditions mean and what do these consist of?
- Conditions that exist at birth or just after
- These consist of:
- Anomalies
- Malformations
- Diseases, which are hereditary or acquired during gestation
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What is the definition of illness/injury/disease?
Abnormal condition of an organism that impairs bodily functions -
2 Paleopathology: Bone biology
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What is the function of Osteocytes?
These are embedded within the bone tissue and serve as the communication network -
What happens during abnormal bone loss?
- Increased osteoclast
- Decreased
osteoblast - Increased osteoclast and decreased
osteoblast - Normal osteoclast and osteoblast but mineralization problem
- Osteogenesis imperfecta
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What is the definition of a non-specific disease marker/non-specific stress marker?
A disease lesion of non-specific cause -
What is a differential diagnosis and how is it done?
- Careful study of the appearance and distribution of the nonspecific marker to possibly determine the cause
- Take into account as many variables as possible
- List all possible diseases
- Suggest the most likely disease
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Which factors can influence the activity of osteoclasts, osteoblasts and osteocytes?
- Activity
- Nutrition
- Age
- Disease
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What is woven bone/fibrous bone?
The first type of bone that gets laid down at thesite of aninjury
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