Lecture systemic sclerosis and myositis

7 important questions on Lecture systemic sclerosis and myositis

Why should combine the diagnostics of primary vs secondary raynaud's (microscopy of nailfold capillaries) with auto antibodies in development of systemic autoimmune disease

You should combine the diagnostics of primary vs secondary raynaud's (microscopy of nailfold capillaries) with auto antibodies in development of systemic autoimmune disease. If both NCM and ANA is negative you are almost 100% no autoimmune disease will developl

How to treat Raynaud's phenomenon

Calcium antagonist, PDE-5 inhibitors.

What does scleroderma (systemic sclerosis) entail.

Thickening and hardening of the skin. Raynauds phenomenon, digital ulcera or pitting scars, teleangiecstasia or spider veins. Calcinosis cutis (skin manifestation), shortness of breath, diarrhea. More a vascular disease
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What is the difference between limited and diffuse systemic scleroderma.

Limited, only the lower legs, lower arms, and face are involved. Limited form CAN have lung involvement. Diffuse cutaneous SSc is the whole body.

What is pulmonal involvement an important sign of?

Interstitial lung disease (ILD), increased shortness of breath, drug couch is and important cause of death and sign of SSc

Progressive difuse systemic sclerorsis; how does it progress?

The skin is very tight, knees cannot be bent, fingers cannot be bent.

What are signs for myositis

Grotton patches on hands and knees, redness around the eyes,  with dermatomyositis you see an erythematous rash on the anterior chest and upper back.

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