Endocrin Toxicology

4 important questions on Endocrin Toxicology

Amitraz & other pesticides(anti vlo& teek)

affect pituarity gland.
(delay) LH release, delayed ovulation,
reduced chances on pregnancy


gossypol (terpenoid) Gossypium spp. (cotton) in seeds

blocks sperm formation
(maturation, motility, necessary enzymes for fertilization ova blocked

Oral contraceptives, estrogen

high dose of estrogen in  the blood-->inhibits oversceretion of gonadothropin ---> less LH. No LH peak = no pregnancy
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zearalenone and its metabolites
Mycotoxin produced by Fusarium spp

hormone-mimicin of estrogen.Related to breast cancer, uterus cancer
and other hormone related deficiencies

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