Tumorbio-5

4 important questions on Tumorbio-5

What is the effect of miRNA?

regulated expression by specific promotors and RNS polymerase II and mRNA stability

What is the effect of direct/indirect MYC TF regulation?

- dna - en mitochondrial metabolism
- proteins involved in enegry productions

What is the effect of Abl?

actin remodelling
cell adhesion and motility
receptor endocytosis and autophagy
DNA damage response and apoptosis
PLAYS a major role in the regulation of cell death after DNA damage!!
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How does Leukemia develop?

1) disruption of maturation of precursor cells
2) clonal development
3) Cumulative results of incidences
4) One or more mutations necessary
5) failure of surveillance function of the immune system

The question on the page originate from the summary of the following study material:

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