Tumorbio-8

7 important questions on Tumorbio-8

What is the effect of CCNE1 mutation?

Cyclin E -> gene amplification & regulates transcription

What is the effect of MYB mutation?

transciptional activator and amplification

What is the effect of SMAD mutation?

allele loss/deletion
  • Higher grades + faster learning
  • Never study anything twice
  • 100% sure, 100% understanding
Discover Study Smart

What is the effect of MYH mutations?

homozygous mutations in the base excision repair pathway gene MYH cause an apparent autosomal recessive adenomatous polyposis syndrome which is called MAP

What is the effect of HNPCC?

lynch syndrome, defect in the MMR DNA genes that maintain the fidelity of DNA during replication

What do the germline defects in MYH have for effect?

prevent the repair of oxidative damage of DNA

What is the ffect of APC being truncated in mitosis?

interaction of the kinetochore with the spindle-apparatus is pertubed

The question on the page originate from the summary of the following study material:

  • A unique study and practice tool
  • Never study anything twice again
  • Get the grades you hope for
  • 100% sure, 100% understanding
Remember faster, study better. Scientifically proven.
Trustpilot Logo