Lecute 1B: The biological basis of heredity Introduction to Human Genetics
14 important questions on Lecute 1B: The biological basis of heredity Introduction to Human Genetics
What are the functions of DNA?
- Replication
- Synthesis proteins (20 amino acids)
What happens at alternative splicing?
What is cutting events?
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What are posttranslational modifications?
What is the driving force of life?
Why does the DNA have a helix structure?
How we measure DNA?
- WGS
- SNP
- Structural variation
- Insertion/deletion
How we measure RNA?
- Single cell/tissue specific expression levels
- RNA sequencing
- RNA expression levels of knows transcripts
What are somatic cells?
What are germ cells?
What does a human cell consist of?5
2. Membrane
3. Cytoplasm
4. Mitochondrium
5. Chromosome
What are 4 differences between DNA and RNA?
2. DNA has Thymine which makes double helix possible, RNA has Uracil, no double helix possible
3. DNA has double stranded where RNA has single stranded
4. RNA molecules are shorter than DNA molecules - rarely more than a few thousand nucleotides
What is non-coding RNA?
How goed mRNA to Protein (translation)?4
2. 4^3 combinations = 64 codons for only 20 amino acids
3. Stop codons: UAA, UAG and UGA
4. Start codon: AUG
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