T cell function and the destruction of cell-associated invaders
5 important questions on T cell function and the destruction of cell-associated invaders
Cytotoxic T cell subsets
Other mechanisms of cellular cytotoxicity
- Cells with antibody receptors Fc-gamma-R1 of 2 can also kill other cells
Classical macrophage activation
- Exposure to bacteria triggers initial activation
- Exposure to IFN-gamma triggers complete acitvation
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Alternative macrophage activation
- M2 cells promote Th2 and tissue repair
Effector T cell memory
- Most of the generated CD8 cells die after infection
- Cells that survive become memory cells
- are CD44 -> express increased amounts of adhesion molecules
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