Organs of the immune system
8 important questions on Organs of the immune system
Primary lymphoid organs
- T lymphocytes mature in the thymus
- B lymphocytes mature in the bone marrow
- in these organs lymphocytes do not encounter antigens and arent stimulated by them
Secondary lymphoid organs
- they are connected to both blood and the lymphoid system
Circulating T cells can leave the bloodstream by two routes
- Memory T cells leave the blood stream through blood vessels in tissues and are carreis to lymph nodes via lymph vessels
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Other secondary lymphoid organs
- primary immune response -> antibodies are mainly produced in the spleen and lymph nodes
- memory cells move into the bone marrow and during a secondary repsonse antibodies emerge from there
Major types of lymphocytes
- T cells (regulatory)
- B cells (generate antibodies)
Lymphocyte surface molecules
- several surface molecules in domestic mammals that have no known homolog in humans or mice
- these are given the prefix WC (workshop cluster)
- a cytometer can recognize cell surface receptors
Molecules regulating lymphocyte function
- antibody receptors (FcRs)
- complement receptors
Other major surface molecules
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