Mechanisms of hormone secretion, action, and response

5 important questions on Mechanisms of hormone secretion, action, and response

What is autocrine signaling?

Te cell responds to their own hormone production. Malignant cancer cells produce GH

How do peptide hormones degrade?

After being released into the circulation proteins are degraded by circulating proteases. When bound to a receptor lysosomal ezymes degrate the hormone. Receptors are often re-used.

Where are catecholamines stored?

In chromaffin granules. These vesicles are reused after catecholamines are released.
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What are G-protein linked receptors

Biggest group of receptors. They transfer hormonal messages into the cell. These receptors have a 7-transmembrane system.

What are channel linked receptors?

These involve rapid synaptic signaling. Opening of ion channels allowing instream of ions. Sodium, GABA, and Bradykin (potassium) work on these receptors.

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